PLENARY SPEAKERS

ICONAN 2018 conference will gather high-profile Nanomedicine and Nanobiotechnology experts to deliver plenary speeches:

Prof. Margherita Morpurgo

Prof. Margherita Morpurgo

Department of Pharmacology – Padova University, Italy

Professor in Pharmaceutical and Medical device Technology at the University of Padova. PhD in Pharmaceutical, she was a post-doctoral fellow at the Weizmann Institute of Science and Visiting Professor at the Mount Sinai medical centre in NY. Her lab develops micro and nano-formulations for drug delivery and diagnostics based on nature-inspired materials. Expert in PEGylation, bioconjugation and biodegradable, multifunctional, self- assembling assemblies. Since 2008, she co-founded Spin-off ANANAS Nanotech, s.r.l. a company devoted to the development of self-assembled poly-avidin nanosystems for diagnostics and drug delivery purposes. Since 2016 she is the University of Padova Rector Delegate for Technology Transfer in the Life Sciences. She contributed to more than 50 papers in peer review journals and to more than 10 international patent/patent applications (H-index Google Scholar: 20).

Talk title: Environment sensitive therapeutic nanosystems

Dr. Paolo Bigini

Dr. Paolo Bigini

Mario Negri Institute for Pharmacological Research, Italy

Dr Paolo Bigini, PhD is an in-staff researchers Scientist at the Mario Negri Institute. He has long experience in neuroscience and pharmacology, with a particular interest in issues related to the evaluation of potential therapeutic strategies in murine models of neuromuscular disorders. In particular, He has been involved in a large number of projects aimed at evaluating the effect of stem cell therapy in mice recapitulating acute and chronic neurodegenerative pathologies. In this context the group led by Dr. Bigini has optimized reliable protocols for the longitudinal stem cells tracking in healthy and pathological areas by the exploitation of superparamagnetic and fluorescent nanoparticles and the exploitation of specific “preclinical imaging protocols” (which associate non-invasive techniques [MRI, FMT, microCT] together with the techniques of histology and pharmacokinetics). He’s following different imaging studies in projects of nanopharmacology and nanotoxicology. Since 2012 He has been coordinating many studies of nanomedicine at the Mario Negri Institute, where is also the Leader of Nanobiology Unit. Paolo Bigini is deeply involved on the care and the welfare of laboratory animals both in his Institute and in other private and public Institutions. He has published more than 50 manuscripts and He has reviewed a large number of papers, mainly in the fields of neuropharmacology, stem cells and nanobiology.

Talk title: From nanotech to nanomed: work in progress

Prof. Michael J. Sailor

Prof. Michael J. Sailor

University of California, USA

Michael J. Sailor is Distinguished Professor of Chemistry and Biochemistry at the University of California, San Diego, and he holds Affiliate Appointments in the Bioengineering, the Nanoengineering, and the Materials Science and Engineering programs at UCSD. Trained as a chemist, Sailor received his training at Harvey Mudd College (B.S.) and Northwestern University (PhD). He is Associate Editor of the journal ACS Sensors, he is a Fellow of the American Association for the Advancement of Science, the U.S. National Academy of Inventors, and the Royal Society of Chemistry.

Talk title: Treatment of Bacterial Infections with Peptide-Targeted Porous Silicon Nanoparticles

Prof. Rabah Boukherroub

Prof. Rabah Boukherroub

Lille 1 University, France

Dr. Rabah Boukherroub received a PhD in chemistry from the University Paul Sabatier in Toulouse, France. He is currently a CNRS research director at the Institute of Electronics, Microelectronics and Nanotechnology (IEMN), University Lille1, France. He is Associate Editor for ACS Applied Materials & Interfaces. His research interests are in the area of functional nanomaterials, surface chemistry, and photophysics of semiconductor/metal nanostructures with emphasis on biosensors and lab-on-chip applications, and development of new tools for studying molecular dynamics in vivo. He is a co-author of 350+ research publications and wrote 25 book chapters in subjects related to nanotechnology, materials chemistry, and biosensors. He has 8 patents or patents pending.

Talk title: Transdermal Drug Delivery: Beyond the State of the Art

Prof. Vicki Stone

Prof. Vicki Stone

Heriot-Watt University, UK

Vicki Stone (BSc PhD FRSB FRSE FRSC) is Director of the Institute of Biological Chemistry, Biophysics and Bioengineering, as well as the Nano Safety Research Group at Heriot-Watt University, Edinburgh. Vicki is also an Honorary Principal Scientist at the Institute of Occupational Medicine. She was the holder of the Royal Society of Chemistries Toxicology Award (2015-16) and the Editor-in-chief of the journal Nanotoxicology (http://informahealthcare.com/nan) for 6 years (2006-2011). Vicki has also published over 165 publications pertaining to particle toxicology over the last 20 years and is recognised by Clarivate Analytics (formerly Thomson Reuters) as one of the top 1% of all researchers in the world for the most cited publications in the field of Pharmacology and Toxicology.

Vicki has provided evidence for the government commissioned reports published by the Royal Society (2003) and the on Environmental Pollution (2008) and she has previously worked as a member of the UK Government Committee on the Medical Effects of Air Pollution (COMEAP) and an advisory board member for Center for the Environmental Implications of NanoTechnology (CEINT; funded by the US Environmental Protection Agency).

The nanotoxicology work at Heriot-Watt University currently involves three new large EU funded projects GRACIOUS, PATROLS and BIORIMA. GRACIOUS (for which Vicki is coordinator) will generate a framework for streamlining the risk assessment by facilitating grouping and read-across of nanomaterials. PATROLS will generate advanced alternative models for assessing the hazards of nanomaterials to humans and other species. BIORIMA will generate a risk assessment framework for nanomedicines. Other funding includes UK Research Councils (NERC, BBSRC and EPSRC), the European Commission (ITS-NANO, ENRHES, ENPRA, InLiveTox, NanoImpactNet, Marina, SUN and Qnano), charities (The Colt Foundation and The Cunningham Trust), the UK Government (http://www.iom-world.org/research/nanoparticles.php) and industry (ECFIA, Byk/Altana, Unilever and GlaxoSmithKline).

Talk title: Streamlining the innovation of nanomedicines and nanomaterials through application of cutting edge hazard approaches

Prof. Sophia Antimisiaris

Prof. Sophia Antimisiaris

Institute of Chemical Engineering FORTH/ICE-HT & University of Patras, Greece

Sophia G. Antimisiaris (http://www.iceht.forth.gr/staff/antimisiaris.html) received her BPharm (1984) and PhD in Pharmaceutics (1988) from Athens University, Greece. She worked as a Post-doc research assistant in the School of Pharmacy of the University of South California, Los Angeles, USA, for 2 years (1989-1990), and then became a Lecturer of Pharmaceutical Technology in the University of Patras, where she is the head of the Laboratory of Pharmaceutical Technology (from 2002), and a full Professor from 2009. During a sabbatical she worked on Liposome Technologies for Advanced Drug Delivery applications as a Visiting Professor in the School of Pharmacy, University of London, in the group of Gregory Gregoriadis from 1992 – 1993. From 2006, after invitation, she is a collaborating member of the Institute of Chemical Engineering of the Foundation of Research and Technology Hellas (FORTH) (http://www.forth.gr/), the largest research Institute in Greece. SGA’s research group focuses on the development of liposomal nanomedicines for controlled and/or targeted drug delivery. She has received funding from National and European sources (FP6, INTERREG, Marie Curie, FP7), as well as from Pharmaceutical Industries. Her group was or is responsible for the development of advanced liposomal formulations in several large collaborative European projects (SHIVA, Euro-PhD in Advanced Drug Delivery Systems, NAD), as well as National projects (LIPArs, SYSTOFAR, NANO-Ins etc.). She is the main author of more than 100 peer-reviewed papers and more than 25 book chapters and review articles. She has mentored more than 25 MSc and 11 PhD students, several postdocs, and participated in the advisory committees of more than 50 Post-graduate students. She is a member of AAPS, CRS (& CRS-Greek Chapter), ILS and other National and International Scientific Societies. She has organized 4 international Workshops on Liposome Technology/Nanomedicines (funded by Erasmus+), and organized or co-organized 5 International conferences. She is currently one of the academic supervisors of NANOMED Erasmus Mundus Joint Master Degree (EMJMD). She has served as Editor Europe of J. Biomedical Nanotechnology and is a member of the editorial board/guest editor of several Journals. She is the inventor of 5 Greek, 1 European, 1 US and 1 World patent. Contact: FORTH-ICE/HT & Dept. of Pharmacy-UPAT, Rio Campus, Rio 26504 Greece. santimis@upatras.gr; santimis@iceht.forth.gr

Talk title: Nanomedicines: Advantages, Accomplishments and Challenges

Prof. Rainer Haag

Prof. Rainer Haag

Institut für Chemie und Biochemie, Freie Universität Berlin, Germany

Rainer Haag, born 1968, is Full Professor in Organic and Macromolecular Chemistry at the Freie Universität Berlin. Since 2008 he is the head of a collaborative research center SFB 765 “Multivalency a chemical organization and action principle”. His research interests are dendritic polymers as highly functional polymeric supports for catalysis, macromolecular nanotransporters for DNA- and drug-delivery and protein resistant material surfaces. In 2004 his group was awarded the young investigator NanoFutur award from the German Ministry of Science (BMBF) and in 2010 the Athur K. Doolittle Award of the American Chemical Society (ACS) for their work on “multifunctional nanotransport systems”. He is also advisor for two start-up companies (nanopartica and Dendropharm) that license the group’s technology. With Dendropharm he received the Innovation award Berlin-Brandenburg 2016. Rainer Haag completed his PhD thesis (1995) on Highly Strained Acepentalene Derivatives with Prof. A. de Meijere, University of Göttingen, Germany. In 1994 he joined the group of Prof. M. Rabinovitz, Hebrew University, Jerusalem (Israel) as a Research Fellow. In 1996-1997 he worked as a Postdoc with Prof. S. V. Ley, University of Cambridge (England) on the total synthesis of Spongistatine and soluble polymeric supports for combinatorial synthesis. As a research fellow (1997-1999) with Prof. G. M. Whitesides, Harvard University, Cambridge (USA) he worked on the electronic properties of self-assembled monolayers, nanostructuring of surfaces and multivalent drugs. From 1999 until 2002 he completed his habilitation on “Dendritic Polymers as High-loading Supports for Organic Synthesis and Drug-Delivery” and was research group leader at the Materials Research Center (FMF) of the University of Freiburg (Mentor: Prof. Rolf Mülhaupt). He is recipient of the ADUC-Habilitanden prize 2000, the Reimund-Stadler prize 2001 and the Heinz-Maier Leibnitz prize 2002 of the German Chemical Society. In 2003 he received the Dozenten Award of the German Chemical Industry. He was a co-founder of Hyperpolymers, a company specialized on dendritic polymers. In May 2003 he became Associate Professor in Organic Polymer Chemistry at the University of Dortmund. In 2004 Rainer Haag accepted a Chair position at the Freie Universität Berlin.

Talk title: Multifunctional Polyglycerol based Nanotherapeutics as potential PEG-Alternatives

Prof. Francesco Stellacci

Prof. Francesco Stellacci

EPFL, Switzerland

Prof. Francesco Stellacci got his degree in Materials Engineering at the Politecnico di Milano in 1998 with Prof. Zerbi. He then moved as a post-doc with Prof. J.W. Perry in the Department of Chemistry at the University of Arizona. In 2002 he became as assistant professor in the Department of Materials Science and Engineering at MIT (Cambridge, USA). There he became associate professor with tenure in 2009. In 2010, he moved as a full professor to EPFL where he holds the Constellium Chair. Stellacci has published more than 130 papers and has more than 15 patent applications. He has won numerous awards, among the Technology Review TR35 ’top innovator under 35’, the Popular Science Magazine ’Brilliant 10’, and the EMRS EU40. He is a Fellow of the Royal Society of Chemistry, of the Global Young Academy, and of the European Academy of Sciences.

Talk title: Broad Spectrum Virucidal Materials

Dr. Xiaoyuan Chen

Dr. Xiaoyuan Chen

National Institute of Biomedical Imaging and Bioengineering (NIBIB), NIH, U.S.A.

Dr. Xiaoyuan (Shawn) Chen received his Ph.D. in Chemistry from the University of Idaho (1999). After two postdocs at Syracuse University and Washington University in St. Louis, he started his Assistant Professorship at the University of Southern California in 2002 and then moved to Stanford in 2004. He moved to NIH in 2009 and became a Senior Investigator and Chief of the Laboratory of Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), NIH. His current research interests include development of molecular imaging toolbox for a better understanding of biology, early diagnosis of disease, monitoring therapy response, and guiding drug discovery/development. His lab puts special emphasis on high-sensitivity nanosensors for biomarker detection and theranostic nanomedicine for imaging, gene and drug delivery, and monitoring of treatment. Dr. Chen has published over 600 peer-reviewed papers (H-index >110) and numerous books and book chapters. He is the founding editor of journal “Theranostics” (2016 IF = 8.766). He was elected as AIMBE Fellow (2017), received ACS Bioconjugate Chemistry Lecturer Award (2016), NIH Director’s Award (2014), NIBIB Mentor Award (2012) and 1000 talent plan B (2010). He is also the Past-President of Chinese-American Society of Nanomedicine and Nanobiotechnology (CASNN) and Past-President of the Radiopharmaceutical Science Council (RPSC), Society of Nuclear Medicine and Molecular Imaging (SNMMI).

Talk title: Cancer Nanotheranostics

Prof. Luisa De Cola

Prof. Luisa De Cola

University of Strasbourg, France

Luisa De Cola is since September 2013 Professor Exceptionnelle at the University of Strasbourg (ISIS) as chair of Supramolecular and Bio-Material Chemistry, and part-time scientist at the INT-KIT, Karlsruhe, Germany. Since 2016 she is also Professor at the Institut Universitaire de France (IUF). She was born in Messina, Italy, where she studied chemistry. After a post-doc at the Virginia Commonwealth University, USA, she was appointed Assistant Professor at the University of Bologna (1990). In 1998 she was appointed Full Professor at the University of Amsterdam, The Netherlands. In 2004 she moved to the University of Muenster, Germany. She is recipient of several awards, the most recent being the IUPAC award as one of the Distinguished Women in Chemistry and Chemical Engineering (2011), the International Prize for Chemistry “L. Tartufari” from Accademia dei Lincei (2015) and the Catalan -Sabatier prize from the Spanish Royal Academy of Science (2015). She was elected in 2014 member of the German National Academy of Sciences Leopoldina and in the same year has been Nominated “Chevalier de la Légion d’ Honneur” by the President of the French Republic, François Hollande. In 2016 she was elected member of the Akademie der Wissenschaften un der Literatur of Mainz. Her main interests are luminescent and electroluminescent complexes and their assemblies and nano-, porous and degradable structures for bio-applications. She has published 330 articles in international peer reviewed journals and filed 36 patents (H index = 62).

Talk title: Hybrid and degradable materials for medical applications

Prof. Albert Van Den Berg

Prof. Albert Van Den Berg

University of Twente, The Netherlands

Albert van den Berg received his MSc in applied physics in 1983, and his PhD in 1988 both at the University of Twente, the Netherlands. From 1988-1993 he worked in Neuchatel, Switzerland, at the CSEM and the University (IMT) on miniaturized chemical sensors. In 1998 he was appointed as part-time professor “Biochemical Analysis Systems”, and later in 2000 as full professor on Miniaturized Systems for (Bio)Chemical Analysis in the faculty of Electrical Engineering and part of the MESA+ Institute for Nanotechnology. In 1994 he initiated together with Prof. Bergveld the international MicroTAS conference series. He published over 400 peer reviewed publications (H=54 WoS, H=70 Google Scholar) a.o. in Science, Nature, PNAS, NanoLetters etc. He received several honors and awards such as Simon Stevin (2002), two ERC Advanced (2008, 2015) and three ERC Proof of Concept (2011, 2013, 2016) grants, Simon Stevin award (engineering sciences), Spinoza prize (2009), Distinguished University Professor (Twente, 2010), Distinguished Professor (South China Normal University SNCU, 2012) and board member of the Royal Dutch Academy of Sciences (KNAW) (2011-2016). In 2014 he was appointed scientific director of the MIRA institute for Biomedical Engineering. In 2017 he became co-PI of the Max Planck – University of Twente Center for Complex Fluid Dynamics.

Talk title: Coming soon

Dr. Toni Andreu

Dr. Toni Andreu

EATRIS, Netherlands

Toni is an M.D. Ph.D specialized in genetics and genomics of rare diseases. He has been working in the field of neuromuscular disorders from the translational perspective of the pipeline, from basic science to the development of cell and animal models and clinical research.
After working in Columbia University in New York on mitochondrial disorders from 1998 to 2001, he moved to Barcelona to create the Neuromuscular Lab at the Vall d’Hebron Research Institute where he became Director of the Neurosciences Research Program.
He has also been extremely active in the field of policy-making and held positions as the Director of the Spanish National Institute of Health Carlos III, creating the national program for personalized medicine. He has also been the CEO of the Bellvitge Hospital, one of the most important University hospitals in Spain, as well as the Director General for Research and Innovation at the Catalan Ministry of Health.
Toni is now the Scientific Director at EATRIS, the European Advanced Infrastructure for Translational Research.

Talk title: Translational Research in medicine – Navigating the maze from lab to patient

Prof. Miguel Oliveira

Prof. Miguel Oliveira

University of Minho, Portugal

J. Miguel Oliveira BSc, PhD (Portuguese, M, 40 years old) is a Principal Investigator “Investigador FCT 2012 and Investigador FCT 2015” at the PT Government Associate Laboratory ICVS/3B’s (http://www.3bs.uminho.pt/users/migueloliveira). He is the Director of Pre-Clinical Research at the FIFA MEDICAL CENTER, Estádio do Dragão, Porto, PT since Fev. 2013 and Pro-Director of the 3B’s Research Group, University of Minho, PT. Currently, he is a Lecturer in Doctoral Program in Tissue Engineering, Regenerative Medicine and Stem Cells (TERM&SC) at UMinho, PT (since Dec. 2013). He is also an Invited lecturer at the Faculty of Medicine, U. Porto (since Sept. 2013) and Dept. of Polymer Eng., UM, PT (2009-present).

Along the years he has focused his work on the field of biomaterials for tissue engineering, nanomedicine, stem cells and cells/drugs delivery. More recently, he set-up a new research line within the ICVS/3B’s on 3D in vitro disease models. As a result of his proficiency, he has published so far more than 250 scientific contributions in scientific journals with referee, being 4 of those review papers produced under invitation. He was approved 15 patents, published 5 books, 2 special issue in scientific journals, and more than 70 book chapters in books with international circulation. He has participated in more than 200 communications in national/international conferences and has been invited/keynote speaker in more than 30 plenary sessions. He has an h-index of 33, i10 of 77 and received more than 4600 citations. He has been awarded several prizes including the prestigious Jean Leray Award 2015 from European Society for Biomaterials for Young Scientists for Outstanding Contributions within the field of Biomaterials. He is very active on the elaboration and scientific coordination of several PT and international funded projects. In addition, he is member of the advisory /editorial board of the Journal Bio-Design and Manufacturing, Journal of Materials Science: Materials in Medicine, International Journal of Tissue Engineering, Journal ISRN Biomaterials, The Journal of Experimental Orthopaedics, Journal “Recent Patents on Corrosion Science”, and referee in more than 40 international journals.

Talk Title: Engineered dendrimer nanoparticles for bone tissue engineering

Prof. Silvio Aime

Prof. Silvio Aime

University of Turin, Italy

Silvio Aime graduated from the University of Turin in 1971. After a stint at the University of East Anglia, he returned to Turin in 1974 where he spent his entire career. He is currently Professor of General and Inorganic Chemistry (Faculty of Sciences, degree course in Biotechnologies), and the head of the NMR laboratory of the Department of Chemistry, and the Center for Molecular Imaging at the University of Torino. Professor Aime’s main research is focused on developing diagnostic agents containing lanthanides or hyperpolarized molecules for applications of magnetic resonance imaging with a particular interest in molecular imaging procedures.

Talk title: Nano-sized MR Imaging agents