S3IC 2020 conference will gather high-profile Sensors, Single-Molecules and Nanosystems experts to deliver plenary speeches:
Prof. Carlos Bustamante
Berkley University, United States
Carlos Bustamante is a Professor of Molecular and Cell Biology, Physics and Chemistry at the University of California, Berkeley, and a Howard Hughes Medical Institute Investigator. Dr. Bustamante received his Bachelor’s and his Master’s in Lima, Peru. He obtained his Ph.D. in biophysics from the University of California, Berkeley.
Dr. Bustamante’s laboratory develops and applies single-molecule manipulation and detection methods such as optical tweezers, magnetic tweezers, and single molecule fluorescence microscopy to characterize the dynamics and the mechanochemical properties of various molecular motors that interact with RNA, DNA, and proteins.
Dr. Bustamante is a Fellow of the American Physical Society, and elected member of the National Academy of Sciences, and the America Academy of Arts and Sciences. He has also been elected to the Board of Directors of the American Association for the Advancement of Science.
Speech Title: Co-temporal Force and Fluorescence Measurements Reveal a Ribosome Gear-shift Mechanism of Translation Regulation by mRNA Secondary Structures
Prof. Cees Dekker
Delft University of Technology, Netherlands
Prof. dr. Cees Dekker (1959) is Distinguished University Professor at Delft University of Technology and KNAW Royal Academy Professor. Trained as a solid-state physicist, he discovered many of the exciting electronic properties of carbon nanotubes in the 1990s. Since 2000 he moved to single-molecule biophysics and nanobiology, with research from studies of DNA loop extrusion and supercoiling to DNA translocation through nanopores. More recently his research has focused on studying chromatin structure and cell division with bacteria on chip, while he is also attempting to ultimately build synthetic cells from the bottom up.
Dekker is an elected member of the Royal Netherlands Academy of Arts and Sciences and fellow to the APS and the IOP. Dekker headed the prestigious Kavli Institute of Nanoscience Delft as Director from 2010-2018. He initiated an entirely new Department of Bionanoscience at Delft and leads the 51M€ NWO Zwaartekracht program NanoFront. He published over 300 papers, received an honorary doctorate, and many prizes such as the 2001 Agilent Europhysics Prize, the 2003 Spinoza award, the 2012 ISNSCE Nanoscience Prize, and the 2017 NanoSmat Prize. In 2006, Delft University appointed him as an Institute Professor. In 2014, Dekker was knighted as Knight in the Order of the Netherlands Lion, and in 2015, he received his second ERC Advanced Grant and the KNAW appointed him as a Royal Academy Professor.
Speech Title: Nanopores, from single-molecule biology to single-molecule protein sequencing
Prof. Harald Giessen
University of Stuttgart, Germany
Harald Giessen (*1966) graduated from Kaiserslautern University with a diploma in Physics and obtained his M.S. and Ph.D. in Optical Sciences from the University of Arizona in 1995 as J.W. Fulbright scholar. After a postdoc at the Max-Planck-Institute for Solid State Research in Stuttgart he moved to Marburg as assistant professor. From 2001-2004, he was associate professor at the University of Bonn. Since 2005, he is full professor and holds the Chair for Ultrafast Nanooptics in the Department of Physics at the University of Stuttgart. He is also co-chair of the Stuttgart Center of Photonics Engineering, SCoPE. He was guest researcher at the University of Cambridge, and guest professor at the University of Innsbruck and the University of Sydney, at A*Star, Singapore, as well as at Beijing University of Technology. He is associated researcher at the Center for Disruptive Photonic Technologies at Nanyang Technical University, Singapore. He received an ERC Advanced Grant in 2012 for his work on complex nanoplasmonics. He was co-chair (2014) and chair (2016) of the Gordon Conference on Plasmonics and Nanophotonics. He was general chair of the conference Photonics Europe (Strasbourg 2018) and is co-chair of the biannual conference NanoMeta in Seefeld, Austria. He is on the advisory board of the journals “Advanced Optical Materials”, “Nanophotonics: The Journal”, “ACS Photonics”, “ACS Sensors”, and “Advanced Photonics”. He is a topical editor for ultrafast nanooptics, plasmonics, and ultrafast lasers and pulse generation of the journal “Light: Science & Applications” of Nature Publishing Group. He is a Fellow of the Optical Society of America. In 2018 and 2019, he was named „Highly Cited Researcher“ (top 1%) by the Institute of Scientific Information. His research interests include Ultrafast Nano-Optics, Plasmonics, Metamaterials, 3D Printed Micro- and Nano-Optics, Novel mid-IR Ultrafast Laser Sources, Applications in Microscopy, Biology, and Sensing.
Speech Title: Topological plasmonics: Watching ultrafast vector movies of plasmonic skyrmions on the nanoscale
Prof. Luke Lee
Harvard University, United States
Speech Title: Coming soon
Prof. David Leigh
The University of Manchester, UK
David Leigh is one of the pioneers of synthetic molecular machinery. Landmark examples from his laboratory include the first synthetic Brownian ratchet molecular motors [Nature 2003, 424, 174; Nature 2007, 445, 523] and the first reversible synthetic molecular motor [Science 2004, 306, 1532]. His group created the first synthetic molecular machines able to perform macroscopic work [Nat. Mater. 2005, 4, 704], invented the first artificial small-molecule motors that, like motor proteins, ‘walk’ along tracks [Nat. Chem. 2010, 2, 96] and also developed the first compound molecular machines having truly complex mechanisms of operation, such as a small-molecule machine that synthesizes peptides with a programmed specific sequence in a manner reminiscent of the ribosome [Science 2013, 339, 189; featured in ‘Breakthroughs-of-the-Year 2013’ Science 2013, 342, 1441]. In the past few years his group have reported the first examples of autonomous chemically-fuelled molecular motors (Nature 2016, 534, 235), used knotting in a molecule to induce allosteric catalysis (Science 2016, 352, 1555), synthesized the most complex molecular knot to date (Science 2017, 355, 159; featured in the 2019 Guinness Book of World Records), introduced the concept of ‘small-molecule robotics’ (Nat. Chem. 2016, 8, 138) and developed a programmable ‘molecular assembler’, described in an accompanying News & Views article as ‘Science fiction becomes fact’ (Nature 2017, 549, 374).
Leigh has received a number of national and international scientific awards, including the Royal Society of Chemistry (RSC) Prizes for Supramolecular Chemistry (2003), Nanotechnology (2005) and the Tilden (2010) and Perkin (2017) Awards, the Spanish Chemical Society (RSEQ) Prize for Chemistry (2007), the Institute of Chemistry of Ireland Award for Chemistry (2005), the Feynman Prize for Nanotechnology (2007), the Izatt-Christensen Award in Macrocyclic Chemistry (2007), the EU Descartes Prize for Transnational Research (2007), the Royal Society Bakerian Medal (2013) and the ISNSCE (International Society for Nanoscale Science, Computation and Engineering) Nanoscience Prize (2019). He was elected a Fellow of the Royal Society (FRS) in 2009. He is a Royal Society Research Professor at the University of Manchester and a 1000 Talents Professor at East China Normal University, Shanghai.
Speech Title: Making the Tiniest Machines
Prof. William E. Moerner - Remote Talk
Stanford University, United States
• 1982: PhD (Physics), Cornell University
o 1981-95: Research Staff Member, IBM Almaden Research Center, San Jose, CA.
o 1993-1994: Guest Professor of Physical Chemistry, ETH Zürich
o 1995-98: Distinguished Professor, Chemistry and Biochemistry, University of California,
o 1998-: Professor, Chemistry; Courtesy Professor, Applied Physics, Stanford University.
• 2007, Member of the National Academy of Sciences
• 2008, Wolf Prize in Chemistry
• 2009, Irving Langmuir Prize in Chemical Physics
• 2013, Peter Debye Award in Physical Chemistry
• 2014, Nobel Prize in Chemistry for super-resolved fluorescence microscopy
• Physical chemistry, biophysics, and the optical properties of single molecules
• Active development of 2D and 3D super-resolution optics and imaging for cell biology
• Imaging studies include protein superstructures in bacteria, structure of proteins in cells,
studies of chromatin organization, and dynamics of regulatory proteins in the primary cilium.
• Measurements of the motions of single proteins, DNA, and RNA in 3D in real time
• Precise analysis of photodynamics of single trapped biomolecules in solution, with
applications to photosynthesis, protein-protein interactions, and transport measurements
Speech Title: Coming soon
Prof. Martin Plenio
Ulm University, Germany
Martin B Plenio is Director of the Institute of Theoretical Physics at Ulm University and founding Director of the newly established Center of Quantum BioSciences. He received his Diploma (1992) and PhD (1994) at Göttingen University. Following his Fedor-Lynen Fellow in the group of Prof. Sir Peter Knight at Imperial College London he received his first faculty appointment at Imperial College in 1998 and eventually rose to Full Professor there in 2003. In 2009 he took up an Alexander von Humboldt Professorship to move to Ulm University. His work covers a broad range of topics, including quantum information science, quantum effects in biological systems, quantum optics, and quantum technologies for quantum simulation and quantum sensing. Recent recognitions of his work include an ERC Synergy grant, international research prizes, the award of Research Building & Center for Quantum-BioSciences and his listing as a Highly Cited Researcher. He is co-founder of NVision Imaging Technologies whose technology builds on his research.
Speech Title: Coming soon
Prof. Claudia Veigel
LMU Munich, Germany
Medicine Universities of Tübingen and Heidelberg, Germany
Royal Society University Research Fellow and Group leader, University of York, UK
Royal Society University Research Fellow and Group leader (tenure), MRC-National Institute for Medical Research London, UK
Full Professor and Chair, Department of Cellular Physiology, Ludwig-Maximilians-University Munich, Germany
Speech Title: Molecular motors – from single myosin molecules to functional ensembles
Prof. Viola Vogel
ETH Zürich, Switzerland
Viola Vogel is Professor of Applied Mechanobiology at the Department of Health Sciences and Technology (D-HEST) at the ETH Zurich and chaired D-HEST from 2018-2020. She holds a PhD in Physics from the University of Frankfurt (1987) and conducted her research at the Max-Planck Institute for Biophysical Chemistry in Göttingen (1980-88) for which she received the Otto-Hahn Medal (1988). After her postdoctoral studies in the Department of Physics at UC Berkeley in nonlinear optics, she started her academic career at the University of Washington Seattle in Bioengineering (1990-2004) and was the founding Director of the Center for Nanotechnology (1997-2003). When moving to ETH Zurich in 2004, she initially joined the Department of Materials and then co-founded D-HEST (2012). With her background in Physics and Bioengineering, she pioneered the rapidly growing field of Mechanobiology and its medical applications, as she discovered many structural mechanisms how mechanical forces can turn proteins into mechano-chemical switches. Such mechanisms are exploited by bacteria, as well as by mammalian cells and tissues to sense and respond to mechanical forces, and if abnormal, can cause various diseases. Her research was recognized by major awards, including an ERC Advanced Grant (2008-13), the International Solvay Chair in Chemistry Brussels 2012. She serves on various international advisory boards in the fields of nanotechnology and bioengineering, including on the White House panel that finalized the US National Nanotechnology Initiative under the Clinton administration (1999), as well as for the Max-Planck Society, A*STAR and CREATE in Singapore and the Wyss Institute, Boston. She was awarded an Honorary Doctor of Philosophy from Tampere University, Finland (2012), she served on the Board of Regents of the Ludwig Maximilian University in Munich (2011-19), on the Board of Trustees of the Gordon Research Conference Organisation since 2018, and is an Einstein Fellow at the Charité Berlin since 2017. She is an elected member of the National Academy Leopoldina since 2018 and of the Berlin-Brandenburg Academy of Sciences since 2019. She is Member of the Jury of the Queen Elizabeth Prize for Engineering since 2014.
Speech Title: Proteins as mechano-chemical switches
Prof. Jörg Wrachtrup
University of Stuttgart, Germany
Joerg Wrachtrup, Professor and director of the 3rd Institute of Physics and the Center for Applied Quantum Science, University of Stuttgart (2000, continuing) as well as Max Planck fellow at the MPI for Solid State Research Stuttgart, has pioneered the field of single spin physics by initially doing the very first single electron and subsequently the first single nuclear spins experiments. By combining optics and spin resonance he discovered defects in insulators, most notably defects in diamond, as a valuable system for quantum information processing in novel type of quantum sensor for electric and magnetic fields. He and his group pioneered application of these novel sensor techniques. His current research interest is geared towards application of quantum enhanced sensing in bio, medical as well as material sciences. Professor Wrachtrup published close to 300 papers in refereed journals with numerous Nature and Science papers, plus reviews in both over the past years. In 2011 and 2017, he was awarded two Advanced Research Grant of the European Research Council, in 2012 he received the Leibniz Price of the German Science Foundation, in 2013 the Bruker Prize and in 2014 the Max Planck Research Award. He is member of the Berlin Brandenburg Academy of Science and has continuously been listed as “Highly Cited Researcher” since 2014.
Speech Title: Coming soon
Prof. Xiaoliang Sunney Xie
Peking University, China
Professor Xiaoliang Sunney Xie is the Lee Shau-kee Professor at Peking University. He is a Fellow of US National Academy of Sciences, a Fellow of US National Academy of Medicine, a Fellow of American Academy of Arts and Sciences, and the Foreign Member of Chinese Academy of Sciences. He had been the Mallinckrodt Professor of Chemistry and Chemical Biology at Harvard University until 2018. He is currently the Director of Biomedical Pioneering Innovation Center at Peking University and the Director of Beijing Advanced Innovation Center for Genomics.
As a pioneer of single-molecule biophysical chemistry, coherent Raman scattering microscopy, and single-cell genomics, he made major contributions to the emergence of these fields. In particular, his inventions in single-cell genomics have been used in in vitro fertilization to benefit thousands of couples in China by avoiding the transmission of monogenic diseases to their newborns.
Prof. Xie received numerous international awards, in particular, Albany Prize in Medicine and Biomedical Research, Peter Debye Award of American Chemical Society and Founders Award for Biophysical Society.
Speech Title: Coming soon
Dr. Leo Gross
IBM Research, Zurich Research Laboratory, Switzerland
Leo Gross, has been with IBM since 2005 at the IBM Research – Zurich Laboratory. First as a postdoc in the group of Gerhard Meyer, since 2009 as a Research Staff Member and since 2020 as Principle RSM. He is the team lead of the atom and molecule manipulation group. In 2019, he was Visiting Professor and Parrain de Promotion at University of Toulouse and in 2020, he is Debye Visiting Chair at Utrecht University. Leo Gross received his PhD in Physics in 2005 from the Free University of Berlin in the group of Prof. Karl-Heinz Rieder. Leo Gross studied Physics at FU Berlin, Tulane University, New Orleans, and at the University Muenster.
- ERC Consolidator Grant for the project “AFM for Molecular Structure Elucidation” (AMSEL), 2016
- Feynman Prize for Nanotechnology, 2012
- Gerhard Ertl Young Investigator Award, 2010
Speech Title: Coming soon
S3IC 2020 conference will bring together researchers in the rapidly advancing field of Single Molecule Sensors and Nanosystems to give invited talks:
Prof. Ara Apkarian
University of California Irvine, United States
V. Ara Apkarian is a Distinguished Professor of Chemical Physics at the University of California, Irvine. He holds BS and PhD degrees in Chemistry from USC and Northwestern. Following a postdoctoral fellowship at Cornell, he joined the Chemistry faculty at UCI in 1983, where he has served as Department Chair (2004-2007), as the founding co-Director of the Chemical and Materials Physics (ChaMP) program, and Director of the NSF Center for Chemistry at the Space-Time Limit (2007-2020). He is a Foreign Member of the National Academy of Sciences of Armenia, a Fellow of APS, AAAS and SPIE, recipient of the Dreyfus Award (1983), Sloan Fellowship (1990), Humboldt Prize (1996), UCI Distinguished Faculty Award for Teaching (2006), USC Distinguished Alumnus (2007), Charles Bennett Award (2008), the ACS Award in Experimental Physical Chemistry (2014), and an Honorary Doctorate from the University of Jyväskylä, Finland (2016). His principle scientific contributions are in photophysics, ultrafast molecular and quantum dynamics, nonlinear optics, spectroscopy, and microscopy. His work has appeared in ~200 peer-reviewed publications. He has organized/co-organized more than 30 scientific conferences and workshops on topics ranging from photophysics, low cryo-chemistry and physics, photodynamics, ultrafast processes, superfluid helium, molecular videography, and chemistry at the space-time limit.
Speech Title: Single molecule devices addressed with atomically confined photons
Prof. Wesley Wong
Harvard University, United States
Wesley Wong is an Associate Professor at Harvard University in the Departments of Biological Chemistry & Molecular Pharmacology and Pediatrics and is an Investigator at the Program in Cellular and Molecular Medicine at Boston Children’s Hospital. His group studies the physical basis behind how biological systems work at the nanoscale, with a focus on the role of mechanical force. To accomplish this, his group develops and applies novel methods in single-molecule manipulation and detection, combining approaches from a variety of disciplines, including physics, molecular biology, chemistry, and engineering.
Dr. Wong received his Ph.D. in Physics from Harvard University. Following this, he was a Rowland Junior Fellow at the Rowland Institute at Harvard University, where he was the Principal Investigator of the Single-molecule Force Studies Group. Current research projects include single-molecule studies of the mechanical regulation of hemostasis, creating DNA origami-based devices for biochemical measurement, and the development of “single-molecule centrifugation” for performing massively parallel single-molecule force measurements in a simple and inexpensive way.
To learn more, visit wonglab.tch.harvard.edu
Speech Title: High-throughput, High-resolution Force Spectroscopy: From the Centrifuge Force Microscope to Programmable DNA Nanoswitches
Prof. Maria Garcia-Parajo
ICFO – the Institute of Photonic Sciences
Maria Garcia-Parajo received her PhD in Physical Electronics in 1993 at Imperial College, London, UK. After a two-years postdoc at the L2M-CNRS, Bagneux, France she obtained a permanent position in the Applied Optics group of the University of Twente, the Netherlands from 1998 to 2005. In 2005 se moved to Barcelona as ICREA Research Professor, first hosted at the IBEC – Institute for Bioengineering of Catalonia and since July 2011 at ICFO-Institute of Photonic Sciences, leading the Single Molecule Biophotonics group. Her research focuses on the development of advanced optical techniques to the study of biological processes at the single molecular level on living cells. She has co-authored more than 170 publications in peer-reviewed international Journals and delivered more than 200 talks at international conferences and workshops upon invitation. She coordinates several international research projects and has been a member of the executive board of the Spanish Biophysical and the International Fluorescence Societies. She has received several prestigious awards including the Young Academy fellowship of the Netherlands Royal Academy of Sciences (1999), the Advanced grant of the Human Frontiers Science Program (2012), Bruker National Prize in Biophysics given by the Spanish Biophysical Society (2017) and Advanced ERC grant 2017. She is currently part of the Gender Committee at ICFO and actively involved in (inter)national actions to promote gender equity in Science.
Speech Title: Nanophotonic tools to resolve nanoscale dynamics on biological membranes
Prof. Xuefeng Guo
College of Chemistry and Molecular Engineering, Peking University, China
Dr. Xuefeng Guo received his Ph.D. degree in Organic Chemistry in 2004 from the Institute of Chemistry, Chinese Academy of Science, Beijing. In 2006, he was awarded the National Top 100 Excellent Ph. D. Thesis Award in China. From 2004 to 2007, he was a joint postdoctoral scientist at the Columbia University Nanocenter, where he worked on single-molecule devices and device physics. He joined the faculty as a professor under “Peking 100-Talent” Program at College of Chemistry and Molecular Engineering, Peking University in January 2008. In 2012, he won the National Science Fund for Distinguished Young Scholars in China. His research interests are focused on single-molecule devices and device physics, flexible/organic electronics, single-molecule biodetection and dynamics, etc. He has over 160 scientific papers, including Science, Chem. Rev., Acc. Chem. Res., Chem. Soc. Rev., Nature Nanotechnol., PNAS, JACS, Angew. Chem. Int. Ed. et. al., and 16 patents.
Speech Title: Challenges and Opportunities in Single-Molecule Electronics
Prof. Amit Meller
Prof. Amit Meller completed his PhD in Physics at the Weizmann Institute of Science (1997) and then moved to Harvard University for his postdoctoral studies with Prof. Daniel Branton. At Harvard he was among the pioneers developing nanopore sensors for single molecule DNA sequencing. He then launched his own research group at the Rowland Institute at Harvard, developing single-molecule techniques, such as nanopores and sm-FRET for novel nucleic acids and proteins characterization. In 2006 Dr. Meller joined Boston University’s department of Biomedical Engineering as an Associate Professor, and in 2010 was appointed as a World-Class University Professor of Biophysics and Chemical Biology at Seoul National University. Currently Prof. Meller is a full professor and associate dean of Biomedical Engineering at the Technion, Haifa (Israel).
Dr. Meller has led a number of internationally recognized, project funded by the Human Frontier Science Program (HFSP), NIH and NSF. He led the German-Israeli Helmholtz Research School SignGene, jointly with leading scientists in Germany and in Israel. Dr. Meller is the director of the first Israeli Center of Excellence (I-Core) in the area of Biological Physics. In 2019 he received the ERC AdG award form H2020. Prof. Meller published and lectured extensively in the areas of nanopore biosensing and single-molecule biophysics. His lab focuses on development and applications of new methods for the study of biological system from the single molecule to live cells. These include three main efforts: (i) Protein translation dynamics and translation initiation biophysics. (ii) Single-molecule biosensors for molecular diagnosis and disease characterization, including early detection of cancer biomarkers, and antimicrobial resistance typing. (iii) Methods development for ultra-sensitive biomolecules sensing in live cells; DNA sequencing and genotyping.
Speech Title: Coming soon
Prof. Felix Ritort
Universitat de Barcelona, Spain
Dr. Felix Ritort carried out his PhD during the years 1989-1991 in theoretical physics in the area of statistical physics. During the years 1992-2002 he made several contributions to the field of disordered systems and nonequilibrium physics. Since 2002 he worked in single-molecule biophysics by manipulating individual nucleic acids and proteins to investigate energy processes in the molecular world. Ritort’s group is recognized worldwide as a leader in applying the finest and most powerful methods to extract accurate quantitative information about thermodynamics and kinetics of molecular interactions. Dr. Ritort has been awarded several prizes for his research: the Distinció de la Generalitat de Catalunya in 2001 for his theoretical research during the years 1991-2000; ICREA Academia Award 2008, 2013 and 2018 for his research as scholar at the University of Barcelona; Bruker Prize in 2013 from the Sociedad de Biofísica de España for his contributions to molecular biophysics research in Spain. He is also chair of the Division of Physics for Life Sciences of the European Physical Society.
Speech Title: Folding Funnel of Protein Barnase Measured with Calorimetric Force Spectroscopy
Prof. Ozgur Sahin
Colombia University, United States
Ozgur Sahin is an Associate Professor of Biological Sciences and Physics at Columbia University.He received his undergraduate degree from Bilkent University and his Ph.D. from Stanford University. His research group is investigating energy conversion in biological nanostructures, developing nanomechanical approaches to determine structures of biomolecular complexes, and studying cell mechanics. Ozgur is recognized for inventing a nanoscale microscope that can visualize mechanical properties of molecules, cells, and materials, which earned him the Grand Prize at the Collegiate Inventors Competition. Ozgur received a Young Scientist Award from the World Economic Forum, a Junior Fellowship from the Rowland Institute at Harvard, and a Packard Fellowship from the David & Lucile Packard Foundation. His research program is also recognized with a U.S. Department of Energy Early Career Award and a New Innovator Award from the National Institutes of Health.
Speech Title: Intramolecular Imaging Using Intermolecular Forces
Prof. Erik Schäffer
University of Tübingen, Germany
Dr. Erik Schäffer is a full professor of Cellular Nanoscience at the University of Tübingen, Germany since 2012. He studied physics at the University of Stuttgart, Germany, and at the University of Massachusetts, Amherst, USA, where he received his M.S. degree in 1997. His doctoral studies were in polymer physics and chemistry at the University of Konstanz, Germany, and the University of Groningen, The Netherlands (1998-2001). He switched to biology for his postdoctoral research at the Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany (2002-2006). There he built his first optical tweezers to study molecular motors. In 2007, he received an Emmy Noether award to establish an independent research group at the Technical University Dresden. In 2010, he was awarded with an ERC Starting Grant and, in 2016, with a prize for bold science from the State of Baden-Württemberg, Germany. Currently, his research in biophysics focuses on developing and applying single-molecule fluorescence and force microscopy techniques – high-resolution optical tweezers and novel trapping probes – to understand how molecular machines, such as kinesin transport motors and DNA repair proteins, work mechanically to fulfill their cellular function.
Speech Title: Germanium nanospheres as high precision optical tweezers probes
Prof. Shimon Weiss
University of California, Los Angeles, United States
Shimon Weiss received his PhD from the Technion in Electrical Engineering in 1989. After a one year post doctorate at AT&T Bell Laboratories, where he worked on ultrafast phenomena in semiconducting devices, he joined Lawrence Berkeley National Laboratory as a staff scientist in 1990, where he continued to work on solid state spectroscopy. In 1994 he re-directed his interest to single molecule biophysics. In 2001 he joined the UCLA Chemistry & Biochemistry and the Physiology departments. In 2016 he also joined the Physics department at Bar Ilan University, Israel (part time).
The Weiss lab has been working on ultrasensitive single molecule spectroscopy methods for over two decades. They were the first to introduce the single molecule FRET method and together with the Alivisatos group the first to introduced quantum dots to biological imaging. They have also developed a variety of single molecule spectroscopy methods, a variety of novel detectors for advanced imaging and spectroscopy, a superresolution imaging method dubbed SOFI, and novel optical imaging tools for single cell physiology. Currently they are developing single inorganic nanoparticle voltage sensors for probing neural networks.
Dr. Weiss has published 180 peer-reviewed papers, and holds 32 issued and 35 published patents. He was awarded the Humboldt Research Award, the Rank Prize in opto-electronics, and the Michael and Kate Barany Biophysical Society Award. He holds the Dean Willard Chair in Chemistry and Biochemistry and he is a Fellow of the Optical Society of America.
Speech Title: Advances in inorganic voltage nanosensors
Prof. Peter Zijlstra
Eindhoven University Of Technology
Peter Zijlstra obtained his MSc degree in Applied Physics at the University of Twente in The Netherlands. In 2009, he received his PhD from Swinburne University of Technology (Melbourne, Australia), where he studied the photothermal properties of single plasmonic nanoparticles with applications in multidimensional optical storage. After a postdoctoral fellowship at Leiden University (The Netherlands) he moved to Eindhoven University of Technology. Since 2012, he leads the research group Molecular Plasmonics at the department of Applied Physics. His research focuses on single-molecule detection using plasmonic nanostructures combined with fluorescent approaches. He combines concepts from super-resolution microscopy, single-particle spectroscopy, and biochemistry, to detect and study DNA and proteins using plasmonic particle-based sensors. He combines single-molecule experiments and numerical modelling to study the fundamentals of plasmon-molecule interactions, whereas applications in e.g. healthcare are explored together with the startup company Helia Biomonitoring.
Speech Title: Coming soon
Prof. Philip Tinnefeld
Philip Tinnefeld is Professor of Physical Chemistry at Ludwig-Maximilians-University since 2017. In 2002, he received a PhD in physical chemistry from the University of Heidelberg. He carried out postdoctoral research at UCLA (USA), in Leuven (Belgium) and Heidelberg. After habilitation in physics at Bielefeld University and three years as associate professor of biophysics at Ludwig-Maximilians-Universität Munich, he was appointed full professor of biophysical chemistry at Braunschweig University of Technology in 2010.
Philip Tinnefeld’s research is inspired by our emerging abilities to study and built matter bottom-up, starting from single molecules. He has contributed to breakthroughs of single-molecule superresolution microscopy by developing the three superresolution techniques dSTORM, Blink Microscopy and DNA PAINT.
In recent innovations, he combined optical single-molecule detection with DNA nanotechnology for self-assembled, functional devices including energy transfer switches, calibration nanorulers, nano-adapters, fluorescence signal amplifiers and molecular force clamps.
Dr. Tinnefeld has authored more than 150 publications and patents. He has been initiator of GATTAquant GmbH, the first company commercializing DNA origami applications.
Speech Title: Single-molecule biosensing enhanced by DNA nanotech