Poster Area
Welcome to the Helicases 2021 poster area.
Posters are available during the whole conference, authors will be available for discussion during the dedicated poster sessions and on the Discussion Room.
You will find below all the posters sorted by day. The “See The Poster” button allows you to see the full version of the poster.
If you have already visited this webpage in the past, we highly recommend refreshing the page in order to get the latest updates.
Tuesday, July 6th
Session 1-A – Plenanry Room
Savannah Weeks
Characterization of the Escherichia coli XPD/Rad3 ironsulfur helicase, YoaA, in complex with the DNA
polymerase III clamp loader subunit, χ
polymerase III clamp loader subunit, χ
Nina Bonde
Searching for synthetic lethality in Escherichia coli strains lacking uup, radD, or recG
Elijah Newcomb
SSB increases Escherichia coli clamp loader lifetime on DNA, and is rapidly remodeled
Ankita Chadda
The Mycobacterium tuberculosis DNA-repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine conserved in other Actinobacteria
Veena Subramanian
Cell-cycle-regulated interaction of the Bloom syndrome helicase with Mcm6 controls DNA replication speed and is essential for the DNA-damage response.
Session 1-B – Room 2
Hamza Balci
A Single Molecule Investigation of Structure and Accessibility of Long Telomeric Overhangs
Lei Li
DEAD box 1 (DDX1) Stabilizes Cytoplasmic mRNAs During Oxidative Stress
Heng-Chi Lee
VASA helicase GLH-1 drives the phase separation of perinculear germ granules to promote the fidelity of piRNA-mediated genome surveillance
Qing Feng
Genome-wide impact of DExH-box RNA helicases on RNA splicing and quality control
Mariarosa De Falco
Intriguing synergic and opposing activities of RecQ-like DNA helicase Hel112 in combination with enzymes involved in different DNA metabolism activities
Session 1-C – Room 3
Aaron Morgan
Kinetics of Nucleotide Binding to the gp16 ATPase
Nora Halgasova
Three charged amino acid residues at the extreme C-terminus of the BFK20 gp41 helicase play a role in the ATPase activity of the protein
Jeannette Kappenberger
How to limit the speed of a motor – the intricate regulation of the XPB ATPase and translocase in TFIIH
Saikrishnan Kayarat
A rotary-mechanism for GTP hydrolysis by the AAA+ protein McrB stimulated by the endonuclease McrC
Tulika Das
Insertion of a flexible linker alters winged helix domain dynamics affecting substrate binding and unwinding activity of human RECQ1
Wednesday, July 7th
Session 2-A – Plenary Room
Emile Alghoul
SLX4 forms SUMOylation factories via liquid phase separation
Nikita Vaulin
Motif I of the Cas3 SF2 helicase domain regulates directionality of Cas3 movement during CRISPR interference and primed adaptation
Sourav Saha
Human DNA/ RNA Topoisomerase TOP3-beta (TOP3B) is coordinated with the DEAD-box Helicases DDX5 and DDX6 to resolve R-Loops
Alexander Duckworth
A 3.2 Ã… structure of the PriA/PriB/replication fork complex reveals mechanistic insight into bacterial DNA replication restart
Sonia Vidushi Gupta
Functional interaction between Sgs1 and Sod2 in the suppression of oxidative-damage-induced chromosomal rearrangements and mitochondrial abnormalities in Saccharomyces cerevisiae
Pedro Heringer
The evolutionary origins of Pif1 helicases from Helitron transposons
Session 2-B – Room 2
Paulina Duhita Anindita
Structural snapshots of ATPase cycle of tick-borne encephalitis virus NS3 helicase
Rebecca Lee
Biochemical studies of the COVID-19 Nsp13 helicase required for coronavirus replication
Marco Halbeisen
Mechanism of RNA mediated phosphate release from the active site of the tick-borne encephalitis virus helicase
Brandon Malone
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex
Dong-Eun Kim
Unwinding of duplex nucleic acids by cooperative translocation of SARS coronavirus helicase nsP13 is modulated with ATP concentration
Session 2-C – Room 3
Martina Valentini
The DEAD-box RNA helicase RhlE2 is a global regulator of Pseudomonas aeruginosa lifestyle and pathogenesis
Wiebke Obermann
The DEAD-box RNA helicase eIF4A is a promising host target for the development of potent broad-spectrum antivirals
Marc Boudvillain
Structural basis for resistance of Mycobacterium tuberculosis Rho to bicyclomycin
Chi-Lin Tsai
EXO5-DNA Structure and BLM Interactions Direct DNA Resection Critical for ATR-dependent Replication Restart
Heinz Nasheuer
The functional cooperation of SV40 T antigen monomers and hexamers is essential for viral DNA replication
Thursday, July 8th
Session 3-A – Plenary Room
Lorena Novoa-Aponte
Analysis of the iron chaperone PCBP1 interactome: intersection of DNA repair and iron trafficking
Remi Fritzen
How XPD helicase responds to DNA damage and base composition
Lubna Yasmin
DNA damage repair and DEAD Box 1 (DDX1) in embryonic development
Megan Behrmann
Directed E. coli DnaB exterior surface mutations effect helicase conformation and regulate behavior to preserve genome stability in vivo
Xiangrong Chen
Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
Robert Simmons
The roles of Hrq1 in ICL repair
Session 3-B – Room 2
Rachel Cueny
Systematically mapping G-quadruplex regulatory elements on E. coli transcripts
Ignacio Mir Sanchis
The structure of self-loading MCM-like helicases encoded by staphylococcal virus satellites reveals unique and conserved motions
Ya-chang Chou
A Mechanical Mechanism for Translocation of Hexameric and Nonstructured Helicases
Nicole Fazio
The E. coli RecBCD nuclease domain regulates DNA binding and helicase activity, but not ssDNA translocation
Jochen Kuper
The Arch domain of XPD: A regulatory multitool that is mechanistically essential for transcription and DNA repair
Friday, July 9th
Session 4-A – Plenary Room
Sonisilpa Mohapatra
Engineering photo-controlled Rep helicase
Jin Yu
Transcription engine and factor protein stepping along DNA revealed from computational microscope
Matthew Thompson
Human DNA Helicase B aids replication of G-quadruplexes
Stefan Mueller
Rapid single-molecule characterisation of nucleic-acid enzymes
Maria Mañosas
Tradeoff between dissipation and uncertainty in helicases
Momcilo Gavrilov
Rapid helicase-SSB assisted isothermal amplification of long DNA fragments
Session 4-B – Room 2
Martina Schroeder
The human DEAD-box helicase 3 interacts with ER-alpha and regulates its activity
Jonathan Schatz
Proteomics Reveal Rocaglate Inhibitors of the eIF4A1 DEAD-box RNA Helicase Remodel the Translation Machinery and Translatome
Florian Pontheaux
Translation of the eIF4B mRNA drives cell division dynamics in sea urchin embryos
Jun Gao
G-quadruplex DNA inhibits unwinding activity but promotes liquid-liquid phase separation by the DEAD-box helicase Ded1p
Anirban Chakraborty
Correlating the conformational dynamics of the DEAD-box helicase eIF4A with translation efficiencies
Linda Krause
Dissecting the role of the eIF4E/5ʹ-cap interaction for eIF4A activity with a model RNA