Programme

Overview of the program (CEST)

  • 13:00                         
  • 13:30                         
  • 14:30                         
  • 15:00                         
  • 16:00                         
  • 17:00                         
  • 17:30                         
  • 18:30-19:00                         

Monday, April 12

  • Course organizers: Presentation of the course and of sponsor (Société Française du Cancer)
  • Maria CARMO-FONSECA, Institute of Molecular Medicine, Lisbon, PT:

    From co-transcriptional splicing to genome instability
  • Discussion with M. Carmo-Fonseca - Chairs: Abderrahmane, Alboushi
  • Hervé LE HIR, IBENS, Paris, FR:

    The multiple facets of the Exon Junction Complex
  • Discussion with H. Le Hir - Chairs: Le Bozec, Shreim, Zeitler
  • Martin DUTERTRE Institut Curie, Orsay, FR:

    Regulation of intronic polydenylation isoforms by genotoxic anticancer agents
  • Discussion with M. Dutertre - Chairs: Li, Lombardi

Overview of the program (CEST)

  • 13:00                         
  • 14:00                         
  • 14:30                         
  • 16:00                         
  • 17:00                         
  • 17:30                         
  • 18:30-19:00                         

Tuesday, April 13

  • Jesper SVEJSTRUP, Francis Crick Institute, London, UK / University of Copenhagen, DK:

    The transcription response to stress and DNA damage
  • Discussion with J. Svejstrup - Chairs: Brothers, Trifault
  • Jeffrey CHAO, FMI, Basel, CH:

    Imagining the life and death of mRNAs in single cells
  • Discussion with J. Chao - Chairs: Chaaban, Celli
  • Davide RUGGERO - KEYNOTE UCSF, San Francisco, US:

    Translating the cancer genome one codon at a time and its therapeutic implications
  • Discussion with D. Ruggero - Chairs: Christopher, Cihlářová, Shi

Overview of the program (CEST)

  • 13:00                         
  • 14:00                         
  • 14:30                         
  • 15:30                         
  • 16:00                         
  • 17:30                         
  • 18:30-19:00                         

Wednesday, April 14

  • Dominique WEIL, IBPS, Paris, FR:

    The GC content of mRNAs shapes their storage in human P-bodies and their decay
  • Discussion with D. Weil - Chairs: de Melo Campos, Devaux
  • Matthias ALTMEYER, University of Zurich, CH

    Dealing with DNA lesions across cell cycle boundaries
  • Discussion with M. Altmeyer - Chairs: Dian, Elzek
  • Monika GULLEROVA, University of Oxford, UK:

    Nascent RNA silencing: novel gene expression regulation pathway
  • Discussion with M. Gullerova - Chairs: Fernandez, Findlay

Overview of the program (CEST)

  • 13:00                         
  • 14:00                         
  • 14:30                         
  • 16:00                         
  • 17:00                         
  • 17:30                         
  • 18:30-19:00                         

Thursday, April 15

  • Fabrizio D'ADDA DI FAGAGNA, IFOM, Milan, FR:

    Non coding RNA synthesis at DNA lesions
  • Discussion with F. d'Adda di Fagagna - Chairs: Hickson, Kajjo, Vargas Abonce
  • Aura CARREIRA, Institut Curie, Orsay, FR:

    BRCA2 promotes DDX5-mediated DNA-RNA hybrid resolution at DNA double-strand breaks to facilitate their repair
  • Discussion with A. Carreira - Chairs: Khanam, Palao
  • Frédéric CHEDIN, UC Davis, US:

    Understanding co-transcriptional R-loop formation and its link to genome instability
  • Discussion with F. Chédin - Chairs: Kwon, Latgé

Overview of the program (CEST)

  • 13:00                         
  • 14:00                         
  • 14:30                         
  • 15:30                         
  • 16:00                         
  • 17:30                         
  • 18:30-19:00                         

Friday April 16

  • Gaëlle LEGUBE, CBI, Toulouse, FR:

    Chromatin and chromosome dynamics at DNA double Strand Breaks
  • Discussion with G. Legube - Chairs: Lemaitre, Biswas
  • Schraga SCHWARTZ, Weizmann Institute of Science, Rehovot, IL:

    Cracking the epitranscriptome
  • Discussion with S. Schwartz - Chairs: Boissière, Chakraborty
  • Anne WILLIS, University of Cambridge, UK:

    Post-transcriptional of gene expression control following toxic injury and in disease
  • Discussion with A. Willis - Chairs: Loock, Lunger, Winter

Overview of the program (CEST)

  • 13:00                         
  • 14:00                         
  • 14:30                         
  • 15:30                         
  • 16:00                         
  • 17:30                         
  • 18:30-19:00                         

Monday, April 19

  • Lori PASSMORE, LMB, Cambridge, UK:

    Mechanistic insights into the cleavage and polyadenylation machinery
  • Discussion with L. Passmore - Chairs: Merida Cerro, Midoun
  • Florence BESSE, IBV, Nice, FR:

    Subcellular targeting of mRNAs
  • Discussion with F. Besse - Chairs: Minello, Moysidou
  • Karlene CIMPRICH - KEYNOTE, Stanford University, US:

    RNA meets DNA: dangerous liaisons in the genome
  • Discussion with K. Cimprich - Chairs: Bofill De Ros, Nebot-Bral, Núñez-Martín

Overview of the program (CEST)

  • 13:00                         
  • 14:00                         
  • 14:30                         
  • 15:30                         
  • 16:00                         
  • 17:00                         
  • 18:00                         
  • 18:30-19:00                         

Tuesday, April 20

  • Benoit PALANCADE, Institut Jacques Monod, Paris, FR:

    The impact of genome organization on transcription-dependent genetic instability
  • Discussion with B. Palancade - Chairs: Kovacs, Qasim
  • Chunlong CHEN, Institut Curie, Paris, FR:

    The impact of transcription-mediated replication stress on genome instability and human disease
  • Discussion with C. Chen - Chairs: Raorane, Saab
  • Dipanjan CHOWDHURY, Harvard Institutes of Medicine, Boston, US:

    Deciphering end resection at a DNA double strand break
  • Discussion with D. Chowdhury - Chairs: Salvador, Shenasa, Singh
  • Debriefing of the course