Day 1 – Tuesday, 6th december 2022

9:00 – 9:30

CET Time, Lithuania +1h

Welcome speeches / Introduction
  • Dr Etienne Snoeck, Deputy Director for Europe, European Research and International Cooperation Department, CNRS

Topic 1: Cancer

Morning Chairperson: Dr. Aušra SASNAUSKIENĖ, Vilnius University Life Sciences Center

9:30 – 10:00

CET Time, Lithuania +1h

Prof. Dr. Juozas KUPČINSKAS, Lithuanian University of Health Sciences (LSMU)-Kaunas Clinics
Microbiome and molecular alterations in gastrointestinal inflammation and cancer

10:00 – 10:30

CET Time, Lithuania +1h

Dr. Judith MINE-HATTAB, The Laboratory of Computational and Quantitative Biology (LCQB)
Single-molecule microscopy during early chromatin remodeling upon DNA damag

10:30 – 11:00

CET Time, Lithuania +1h

Dr. Jan Aleksander KRASKO and Dr. Olha KARAMAN, National Cancer Institute
Cytokine-induced killer cells and bacterial lectins: new opportunities for cancer therapy (the presentation will be given by Dr. Jan Aleksander KRASKO)

11:00 – 11:15

CET Time, Lithuania +1h

Coffee break (15min)

11:15 – 11:45

CET Time, Lithuania +1h

Dr. Jérémie ROUX, Institute of Molecular and Cellular Pharmacology
Coupling dynamic imaging and in situ isolation of the same single-cell, to profile the non-genetic determinants of predicted drug-tolerant cells with fate-seq

11:45 – 12:15

CET Time, Lithuania +1h

Dr. Mindaugas VALIUS, Vilnius University Life Sciences Center
Proteomics for the elucidation of anticancer drug resistance and drug repurposing

12:15 – 13:30

CET Time, Lithuania +1h

Lunch break (1h15)

Afternoon Chairperson: Laura PĖKIĖNĖ, NCP Horizon Europe (Health, Cancer mission); Research Council of Lithuania

13:30 – 14:00

CET Time, Lithuania +1h

Dr. Linas MAŽUTIS, Vilnius University Life Sciences Center
Tackling tumor and immune system heterogeneity using scRNA-Seq

14:00 – 14:30

CET Time, Lithuania +1h

Aurélie TCHOGHANDJIAN, Institute of Neurophysiopathology
Smac mimetic as pan-cellular therapy in glioblastoma

14:30 – 15:00

CET Time, Lithuania +1h

Dr. Andrius ŽUČENKA, Vilnius University Hospital Santaros Klinikos
Biomarker based research of new treatment approaches to relapsed and refractory acute myeloid leukemia

15:00 – 15:30

CET Time, Lithuania +1h

Dr. Eddy PASQUIER
Reverse molecular pharmacology: using existing drugs to discover novel vulnerabilities in refractory cancer

Day 2 – Wednesday, 7th december 2022

Topic 2: Neurodegenerative diseases

Morning Chairperson: Dr. Emmanuel BROUILLET, Research Director at CNRS, Paris

9:00 – 9h30

CET Time, Lithuania +1h

Prof. Dr. Vilmantė BORUTAITĖ, Lithuanian University of Health Sciences (LSMU)-Kaunas Clinics
Neurotoxic effects of extracellular tau and other amyloidogenic proteins

9:>30 – 10:00

CET Time, Lithuania +1h

Dr. Marc DHENAIN, Laboratory of neurodegenerative diseases at the Molecular Imaging Center (MIRCen)
Iatrogenic transmission of β-amyloid and tau proteins: Importance for clinical and biomedical research on Alzheimer’s disease

10:00 – 10:30

CET Time, Lithuania +1h

Dr. Augustas PIVORIŪNAS, Centre for Innovative Medicine
Extracellular vesicles as a potent therapeutic tool against Parkinson’s disease

10:30 – 10:45

CET Time, Lithuania +1h

Coffee break (15min)

10h45 – 11:15

CET Time, Lithuania +1h

Dr. Marie-Claude POTIER
Neuropathological differences between Down syndrome and familial Alzheimer’s disease with APP duplication: role of endothelial cells in cerebral amyloid angiopathy

11:15 – 11:45

CET Time, Lithuania +1h

Dr. Rima BUDVYTYTĖ, Vilnius University Life Sciences Center
The interaction of amyloid ß oligomers with lipid membranes: implications for neurodegeneration

11:55 – 12:15

CET Time, Lithuania +1h

Dr. Hélène MARIE, Institute of Molecular and Cellular Pharmacology (IPMC)
Amyloid precursor protein peptides: physiological modulators of neuronal signaling

12:15 – 13:30

CET Time, Lithuania +1h

Lunch break (1h15)

Topic 3: Infectious Diseases

Afternoon Chairperson: Dr Sylvie GUERDER, Research Director at CNRS, Toulouse

13:30 – 14:00

CET Time, Lithuania +1h

Dr. François TROTTEIN, Center of Infection and Immunity of Lille
Impact of respiratory viral infections on gut microbiota’s composition and functionality : from short chain fatty acids to glycolipids

14:00 – 14:30

CET Time, Lithuania +1h

Prof. Dr. Auksė MICKIENĖ and Vytautas GRIŠKA, Lithuanian University of Health Sciences & Department of Infectious diseases of Lithuanian University of Health Sciences Kaunas Hospital
A prospective study on the long-term outcome and pathogenesis of tick-borne encephalitis/Lithuanian University of Health Sciences (LUHS) and LUHS Kaunas Hospital, Department of Infectious Diseases

14:30 – 15:00

CET Time, Lithuania +1h

Dr. Nicolas PERSONNIC, Centre international de recherche en infectiologie (CIRI)
Single-cell dynamics and persistence of Legionella pneumophila

15:00 – 15:15

CET Time, Lithuania +1h

Coffee break (15min)

15:15 – 15:45

CET Time, Lithuania +1h

Dr. Gytis DUDAS, Vilnius University Life Sciences Center
Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions

15:45 – 17:00

CET Time, Lithuania +1h

Roundtable: Discussion on how to reinforce the collaboration (institutions representatives) and concluding remarks
CNRS representatives:

  • Emmanuel BROUILLET, Head, Europe and International Affairs, INSB, CNRS
  • Etienne SNOECK, Director for European Affairs, CNRS

Lithuanian representatives:

  • Kornelija BACVINKIENĖ, Programme Coordinator for the Lithuanian–French bilateral cooperation Programme; Research Council of Lithuania
  • Aurelija POVILAIKĖ, NCP Horizon Europe (ERC and Widening); NCP Coordinator Research Council of Lithuania
  • Sigita AUVERTIN, NCP Horizon Europe (Health); Research Council of Lithuania
  • Laura PĖKIENĖ, NCP Horizon Europe (Health, Cancer mission); Research Council of Lithuania
  • Tadas TUMĖNAS, Head of Lithuanian Research Development and Innovation Liaison Office in Brussels