Program
Some new features of this first virtual version of MoTEC:
The first is the introduction of informal meetings between PIs from our community and students or young researchers called “Meet the experts” in the program. No less than 8 colleagues have accepted to take part in this exercise.
Why: The goal is to create a time of informal discussion (30 min) between young people and an expert who has a lot of experience in managing a research group, writing grants, publishing articles by senior authors, designing and teaching classes, etc… all that is needed to start after a PhD and also advice on how to choose your postdoc.
When: at the beginning and in parallel of each poster session (duration 30 min)
Where: in dedicated rooms on the Gather virtual platform.
The second is the possibility given to several of you to present in the form of short pre-recorded videos, a teaser of your poster.
Each day, we have selected 4 people on a similar theme. After the broadcasting of the 4 videos, a time of exchange and discussion between the audience and the 4 presenters will be planned. The discussion can continue during the poster session that follows.
In order to allow the greatest fluidity during the poster sessions, a number is assigned to each participant with a poster and the day during which he or she must be present. This information will be made available soon on the website in the “poster” tab.
Schedule overview (CEST)
- 3:00 PM
- 3:15 PM
- 4:00 PM
- 4:25 PM
- 4:50 PM
- 5:10 PM
- 5:30 PM
- 5:50 PM
- 6:15 PM
- 7:45 PM
September 27th, 2021
- Welcome message
- Opening Lecture
Russ Hille
University of California, USA
How we got to Now: Recent Progress in Mo and W Enzymes - Talk 1
Martin L. Kirck
University of New Mexico, USA
The Molybdenum Cofactor, Cofactor Sulfuration, and Mo-Sulfido Contributions to C-H Bond Activation - Talk 2
Nadia C. Mösch-Zanetti
University of Graz, Austria
Nucleophilic Attack on Acetylene in Biomimetic Tungsten and Molybdenum Complexes - Coffee break
- Talk 3
Matthias Boll
University of Freiburg, Germany
Structure and function of a 1 MDa, electron-bifurcating, and tungstopterin containing benzene ring reductase - Talk 4
Agnieszka Winiarska
Polish Academy of Sciences, Poland
A new type of hydrogenase - Tungsten Aldehyde Oxidoreductase from Aromatoleum aromaticum - Poster session 1
Flash Posters
Soniya Ahammad/Madeleine Ehweiner/Filipa Engrola/Mikayla Metzger - Poster session & Meet the experts
Partha Basu and Sharon Burgmayer - End of meeting Day 1
Schedule overview (CEST)
- 2:00 PM
- 2:25 PM
- 2:50 PM
- 3:10 PM
- 3:30 PM
- 3:45 PM
- 4:05 PM
- 4:25 PM
- 4:45 PM
- 5:00 PM
- 5:20 PM
- 5:40 PM
- 6:10 PM
- 7:30 PM
September 28th, 2021
- Talk 5
Ulrike Kappler
The University of Queensland, Australia
S-oxide reductases as determinants of bacterial fitness and pathogenicity - Talk 6
Stéphane Grimaldi
Aix-Marseille University, France
Reaction mechanism of sulfite oxidizing enzymes: a combined structural and spectroscopic study of Thermus thermophilus sulfite dehydrogenase - Talk 7
François Feron
Aix-Marseille University, France
Autism: what’s wrong with molybdenum enzymes? - Talk 8
Tamaki Suganuma
Stowers Institute for Medical Research, USA
MOCS2 links purine metabolism to nucleoli function - Coffee break
- Talk 9
Sharon Burgmayer
Bryn Mawr College, USA
Exploring Model Complexes with Pyranopterin Dithiolene Ligands: Consequences of Pterin Methylation - Talk 10
Jin Yang
The University of New Mexico, USA
Addressing Ligand-Based Redox in Molybdenum-Dependent Methionine Sulfoxide Reductase - Talk 11
Henrique S. Fernandes
Universidade do Porto, Portugal
Exploring the Nitrate and Nitrite Reductase Activity of Xanthine Oxidase – a QM/MM study - Coffee break
- Talk 12
Filipa L. Sousa
University of Vienna, Austria
Diversity and distribution of Moco-complexes within prokaryotes - Talk 13
John F. Stolz
Duquesne University, USA
The Respiratory Selenite Reductase and the Evolution of the DMSO Reductase Family of Enzymes - Poster session 2
Flash Posters
Malin Eh/Constanze Pinske/Thomas Reed/Anna Rovaletti - Poster session & Meet the experts
Martin Kirk and Ines Pereira - End of meeting Day 2
Schedule overview (CEST)
- 3:00 PM
- 3:25 PM
- 3:50 PM
- 4:10 PM
- 4:30 PM
- 4:50 PM
- 5:10 PM
- 5:30 PM
- 6:00 PM
- 7:30 PM
September 29th, 2021
- Talk 14
Günter Schwarz
University of Cologne, Germany
Maturation, function, and deficiencies of mitochondrial sulfite oxidase - Talk 15
Inês A. C. Pereira
Universidade Nova de Lisboa, Portugal
Spectroscopic and structural studies of the W-dependent formate dehydrogenase from Desulfovibrio vulgaris Hildenborough - Talk 16
Ulf Ryde
Lund University, Sweden
Computational studies of nitrogenase - Talk 17
Zhi-Yong Yang
Utah State University, USA
The Electronic Structure of FeV-cofactor in Vanadium-Dependent Nitrogenase - Coffee break
- Talk 18
Anne Walburger
Aix-Marseille University, France
Identification and characterization of a non-canonical menaquinone linked Formate dehydrogenase - Talk 19
Olivier Lemaire
MPI for Marine Microbiology, Germany
Capturing or releasing CO2: how do methanogenic archaea orient their tungsto/molyboenzymes reaction? - Poster session 3
Flash Posters
Ahmed Hassan/Joern Krausze/Nevena Maslac/Maria Reichenbach - Poster session & Meet the experts
Günter Schwarz and Silke Leimkühler - End of meeting Day 3
Schedule overview (CEST)
- 3:00 PM
- 3:25 PM
- 3:50 PM
- 4:10 PM
- 4:30 PM
- 4:50 PM
- 5:10 PM
- 5:30 PM
- 6:00 PM
- 7:30 PM
September 30th, 2021
- Talk 20
Bernd Clement
University of Kiel, Germany
mARC: From a prodrug activating enzyme over a drug metabolizing enzyme to a drug target - Talk 21
Silke Leimkühler
The University of Potsdam, Germany
Exploring the functional versatility of the molybdenum cofactors by their insertion into molybdoenzymes - Talk 22
Kurt Warnhoff
Sanford research, USA
Molybdenum cofactor transfer from bacteria to the nematode C. elegans - Talk 23
Thomas W. Hercher
Technical University of Braunschweig, Germany
Re-assessing the dynamics of Moco biosynthesis in a yeast engineered to synthesize Moco - Coffee break
- Talk 24
Markus Ribbe
University of California, USA
Tracing the Incorporation of the “9th Sulfur” into the Nitrogenase Cofactor Precursor with Selenite and Tellurite - Talk 25
Yilin Hu
University of California, USA
Evidence of substrate binding and product release via belt-sulfur mobilization of the nitrogenase cofactor - Poster session 4
Flash Posters
Gregor Blaha/Marta Meneghello/Ana Rita Oliveira/Alexandre Uzel - Poster session & Meet the experts
Markus Ribbe and Ralf Mendel - End of meeting Day 4
Schedule overview (CEST)
- 3:00 PM
- 3:25 PM
- 3:50 PM
- 4:10 PM
- 4:30 PM
- 4:50 PM
- 5:35 PM
- 5:50 PM
October 1st, 2021
- Talk 26
Betül Kaçar
University of Arizona, USA
Elucidating the origin and evolution of nitrogenases: Implications for early life and environment - Talk 27
Partha Basu
IUPUI, USA
Kinetic control of endogenous ligation to molybdenum in DMSOR family - Talk 28
Cristiano Mota
Universidade Nova de Lisboa, Portugal
The inhibition mechanisms of human aldehyde oxidase by STD-NMR and X-ray crystallography - Talk 29
Kenichi Yokohama
Duke University, USA
Mechanism of carbon skeleton formation in the molybdenum cofactor biosynthesis - Coffee break
- Closing Lecture
Ralf R. Mendel
Technical University of Braunschweig, Germany
Quo vadis molybdenum enzyme research? - Closing remarks
- End of meeting Day 5
Important Deadlines
July 15, 2021 : Submission of abstract for oral or poster presentation (to be selected for a flash presentation)
July 16, 2021 : Acceptance notification (oral and flash)
July 22, 2021 : Confirmation of acceptance for oral presentation of selected speakers
July 23, 2021 : Publication of the scientific program
September 21, 2021 : Submission of recorded presentation for selected poster presenters + End of registration
- Provisional list of invited speakers
- Prof. Russ Hille, opening keynote lecture
- Prof. Ralf R Mendel, closing keynote lecture
- Prof. Partha Basu
- Prof. Bernd Clement
- Dr. Stéphane Grimaldi
- Prof. Betül Kaçar
- Prof. Ulrike Kappler
- Prof. Martin L Kirk
- Prof. Silke Leimkühler
- Prof. Nadia C Mösch-Zanetti
- Prof. Inês AC Pereira
- Prof. Markus W Ribbe
- Prof. Guenter Schwarz
- TOPIC
- The scientific areas that will be covered are:
- 1. Synthesis of Mo or W cofactors and models
- 2. Enzyme structure and function
- 3. Cell physiology of Mo/W enzymes
- 4 Host microbe interaction and virulence
- 5. Impact on health, disease and environment
- 6. Technological applications
Leading scientists from outside the MoTEC-community have also been invited to participate and cover important emerging fields.
Lectures will be followed by an on-stage discussion session and will be recorded and made available to all the participants during the conference.
Poster contributions in all the scientific areas mentioned above are encouraged. We will create a professional interactive online environment for poster viewing where each poster will have its own breakout room – open during the entire conference to accommodate all time zones. Poster presenters selected from the abstracts will be invited to give a three-minute poster flash presentation to promote their work.